Deformity of the tear trough region, which can occur during the aging process, can result in dark shadows under the eyes and a fatigued appearance. Augmentation of the tear trough is challenging because of the thin skin and lack of fat in the region.
Adding volume to the tear trough region with a dermal filler is a nonsurgical procedure with minimal discomfort to the patient. Dermicol-P35 (Evolence; Ortho Dermatologics, Skillman, NJ) is a new, ribose crosslinked, highly purified, porcine-based collagen filler that does not require prior skin testing and has shown improved persistence compared with bovine collagen-based dermal fillers.
In this article, we present the clinical outcomes of patients who have received treatment with a novel ribose crosslinked porcine collagen dermal filler for the correction of tear trough deformity.
"Correction of tear trough deformity with novel porcine collagen dermal filler (Dermicol-P35)"
Aesthet Surg J. 2009 May-Jun; 29(3 Suppl): S9-S11Goldberg DJ (Hubmed.org)
Related:
Microdermabrasion: The Use of Microdermabrasion for Acne
Microdermabrasion: A Prospective Controlled Assessment
Microdermabrasion: Combining superficial glycolic acid peels
Highlight :
Timepeel Diamond Microdermabrasion Machine Treatments | The FBL-U Crystal & Diamond Microdermabrasion Equipment | New and used, Susan Lucci Microdermabrasion Treatment | Do at home microdermabrasion kits really work?
Estrogen deficiency may contribute to extracellular matrix turnover in skin. This has led previous authors to postulate that aged skin heals less efficiently when compared to younger skin. Also, cigarette smokers have been shown to heal less efficiently than nonsmokers.
Matrix metalloproteinase (MMP)-13, an enzyme that participates in the degradation of the extracellular matrix, has been implicated in physiologic aging and wound healing. This study investigates the effects of smoke exposure and estrogen deficiency on MMP-13 in young and aged female mouse skin.
Young and aged female C57Bl/6J mice were ovariectomized. They were then randomly administered either 17beta-estradiol (E2) or placebo pellets. Half the animals in each age group were further randomized to exposure to cigarette smoke for a period of 6 months. Smoking and estrogen deficiency increased MMP-13 protein and activity in aged skin.
The tissue inhibitors of metalloproteinases, which inhibit MMPs, activity was unchanged across all groups. E2 replacement decreased the actual level of MMP-13 protein and activity. We also found an increased collagen content and decreased ER receptor protein level in aged, smoke-exposed female mice.
Our experimental data show that tobacco smoke exposure and estrogen deficiency are additive risk factors for promoting increased activity of MMP-13 in aged skin. These findings suggest that MMP-13 functions as a mediator of smoke-induced skin injury in susceptible, aged experimental female mice.
"Estrogen Deficiency and Tobacco Smoke Exposure Promote Matrix Metalloproteinase-13 Activation in Skin of Aging B6 Mice"
Ann Plast Surg. 2009 Jul 13; Kassira N, Glassberg MK, Jones C, Pincus DJ, Elliot SJ, Fritz JR, Karl M, Thaller S (Hubmed.org)
Related:
Microdermabrasion: Facial skin rejuvenation
Microdermabrasion: Bridging Medicine and Media to Enhance
Medical Microdermabrasion: Microdermabrasion In The Body
Highlight :
Beuty With Diamond Microdermabrasion Treatments | Skin Management Beauty Microdermabrasion Equipment | About Susan Lucci Microdermabrasion TreatmenT kit?? | Ultimate Facial Home Microdermabrasion Kits
Recently, both clinical and bench research has begun to provide scientific validation for the use of certain botanical ingredients. Related findings regarding proposed biological mechanisms of action have translated into clinical practice.
Botanical compounds for which dermatologic and cosmetic applications have emerged include: olive oil, chamomile, colloidal oatmeal, oat kernal extract, feverfew, acai berry, coffee berry, curcumin, green tea, pomegranate, licorice, paper mulberry, arbutin, and soy. Many of these botanical sources offer biologically active components that require further in vitro and in vivo investigation in order for us to properly educate ourselves, and our patients, regarding over-the-counter products based on these ingredients.
"Natural ingredients in cosmetic dermatology
J Drugs Dermatol. 2009 Jun; 8(6 Suppl): s5-9Baumann L, Woolery-Lloyd H, Friedman A (Hubmed.org)
Related:
Medical Microdermabrasion: Superficial chemical peels
Microdermabrasion: A Prospective Study of Efficacy of N-Lite Laser
Medical Microdermabrasion: Microderm Peel : How Much Long Is
Highlight :
Natural Diamond Microdermabrasion for Home Use | Silhouet Tone Derma Pod Microdermabrasion Equipment | Youthful Essence by Susan Lucci Microdermabrasion Treatment | Reviews of home Microdermabrasion Kits
