tag:blogger.com,1999:blog-56013798922803821922012-01-05T20:46:37.896-08:00Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comBlogger2481100tag:blogger.com,1999:blog-5601379892280382192.post-31992944349092926942009-10-15T15:56:00.000-07:002009-11-28T05:01:15.726-08:00

Deformity of the tear trough region, which can occur during the aging process, can result in dark shadows under the eyes and a fatigued appearance. Augmentation of the tear trough is challenging because of the thin skin and lack of fat in the region.Adding volume to the tear trough region with a dermal filler is a nonsurgical procedure with minimal discomfort to the patient. Dermicol-P35 (

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-42624548796114834412009-10-06T15:46:00.000-07:002009-11-28T05:01:15.730-08:00

Estrogen deficiency may contribute to extracellular matrix turnover in skin. This has led previous authors to postulate that aged skin heals less efficiently when compared to younger skin. Also, cigarette smokers have been shown to heal less efficiently than nonsmokers.Matrix metalloproteinase (MMP)-13, an enzyme that participates in the degradation of the extracellular matrix, has been

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-75979367555408496232009-10-01T17:42:00.000-07:002009-11-28T05:01:15.732-08:00

Recently, both clinical and bench research has begun to provide scientific validation for the use of certain botanical ingredients. Related findings regarding proposed biological mechanisms of action have translated into clinical practice.Botanical compounds for which dermatologic and cosmetic applications have emerged include: olive oil, chamomile, colloidal oatmeal, oat kernal extract, feverfew

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-84715888174843160772009-09-14T17:36:00.000-07:002009-11-28T04:01:53.469-08:00

The periorbital area is a key wrinkle-prone region, where the first signs of aging usually appear.AIMS:To demonstrate the ability of new anti-aging moisturizing products to improve overall smoothness and wrinkle depth appearance in the periorbital region via the Fast Optical in vivo Topometry of Human Skin (FOITS).METHODS:Two double-blind, randomized, controlled, split-face studies (n = 42, Study

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-55082967894597907852009-09-12T15:58:00.001-07:002009-11-28T04:12:21.852-08:00

Constipation is a common problem in children, and when it becomes chronic fecal impaction, overflow soiling and megarectum may develop. Children with chronic idiopathic constipation (IC) may not respond to conventional treatments of laxatives, enemas, and toilet training. The aims of the study were to evaluate the long-term outcome of transcutaneous needle-free injection of botulinum toxin (TNFBT

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-39099978333096856152009-09-11T17:52:00.001-07:002009-11-28T04:18:39.533-08:00

Infraorbital dark circles refer to the conditions that present with darkness of the infraorbital eyelids. Although it is not a medical concern, it can be a cosmetic concern for a large number of individuals. Moreover, clear definition and possible causes have not been elucidated.OBJECTIVE:To review the possible causes and treatment options for infraorbital dark circles.METHODS:The article is

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-31849009231141063062009-09-10T23:34:00.001-07:002009-11-28T04:25:15.129-08:00

Primary human aging may be associated with augmented Rho-kinase (ROCK)-mediated contraction of vascular smooth muscle and ROCK-mediated inhibition of nitric oxide synthase (NOS). We hypothesized that the contribution of ROCK to reflex vasoconstriction (VC) is greater in aged skin.Cutaneous VC was elicited by 1) whole-body cooling (Tsk=30.5 degrees C) and 2) local norepinephrine (NE) infusion (

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-41283936375363127632009-09-10T17:43:00.001-07:002009-11-28T04:29:05.609-08:00

Massively parallel pyrosequencing of the small subunit (16S) ribosomal RNA gene has revealed that the extent of rare microbial populations in several environments, the 'rare biosphere', is orders of magnitude higher than previously thought.One important caveat with this method is that sequencing error could artificially inflate diversity estimates. Although the per-base error of 16S rDNA amplicon

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-45322490937379672322009-09-09T23:26:00.001-07:002009-11-28T04:35:44.563-08:00

The dermal degeneration accompanying photoaging is considered to promote skin roughness features such as wrinkles. Our previous study demonstrated that polarization-sensitive spectral domain optical coherence tomography (PS-SD-OCT) enabled noninvasive three-dimensional evaluation of the dermal degeneration of photoaged skin as a change in dermal birefringence, mainly due to collagenous

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-51245857037497828532009-09-09T02:40:00.001-07:002009-09-09T02:40:19.348-07:00

Int J Cosmet Sci. 2009 Sep 1; Dumont S, Cattuzzato L, Trouvé G, Chevrot N, Stoltz CSynopsis The mode of action of two cosmetic active ingredients (AIs), palmitoyl glycine (PG) and cocoyl alanine (CA) was studied with cDNA array experiments and quantitative PCR confirmations, which were performed on experimentally aged human fibroblasts. These preliminary studies revealed complementary profiles.

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-75518557156789287482009-09-08T17:27:00.001-07:002009-09-08T17:27:55.846-07:00

Plast Reconstr Surg. 2009 Sep; 124(3): 826-35McCluskey PD, Constantine FC, Thornton JFBACKGROUND: A full-thickness skin graft is generally not considered the ideal replacement for the thick, sebaceous skin of the nasal tip, ala, lower sidewalls, or dorsum. Instead, many clinicians prefer to reconstruct these defects with local or axial composite flaps that incorporate skin, subcutaneous tissue,

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-52018088028224212352009-09-05T16:27:00.001-07:002009-09-05T16:27:57.373-07:00

J Cell Mol Med. 2009 Sep 1; Mimeault M, Batra SKRecent advances in skin-resident adult stem/progenitor cell research have revealed that these immature and regenerative cells with a high longevity provide critical functions in maintaining skin homeostasis and repair after severe injuries along the lifespan of individuals. The establishment of the functional properties of distinct adult stem/

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-3646723650812381342009-09-02T08:07:00.001-07:002009-09-02T08:07:51.913-07:00

Aesthet Surg J. 2009 Jul-Aug; 29(4): 264-71Man DBACKGROUND: The telltale signs associated with facelift procedures, including tightening of the lower face (lateral sweep), visible scars, a distorted hairline, and the "pixie ear" deformity are grounds for concern among both patients and aesthetic surgeons. It is the author's belief that facelift results can be improved with correct positioning of

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-69823303309901615322009-08-28T22:17:00.001-07:002009-08-28T22:17:41.493-07:00

Dermatol Surg. 2009 Aug 25; Marmur ES, Taylor SC, Grimes PE, Boyd CM, Porter JP, Yoo JYBACKGROUND Recently, the cosmetic market has seen an increase in the options for treatment for people with dark skin. OBJECTIVES This study evaluates the use of calcium hydroxylapatite (CaHA), a dermal filler indicated for the correction of moderate to severe facial wrinkles and folds, including the nasolabial

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-91574109417490794132009-08-28T16:19:00.001-07:002009-08-28T16:19:35.626-07:00

Dermatol Surg. 2009 Aug 25; Marmur ES, Al Quran H, DE Sa Earp AP, Yoo JYBACKGROUND The process of skin aging is not limited to the face but involves every part of the body, including the hands. A common manifestation of aging of the hands is the loss of volume, which occurs as the skin loses its subcutaneous fat. Injectable dermal fillers have surfaced as a popular method to address such

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-9536320069806851502009-08-26T16:11:00.001-07:002009-08-26T16:11:11.424-07:00

Clin Dermatol. 2009 Sep-Oct; 27(5): 479-84Singh RP, Agarwal RCosmeceuticals are used for nourishing and improving the appearance of the skin and are also documented as effective agents for treating various dermatologic conditions. Cosmeceutical preparations from herbal origin are most popular among consumers because these agents are mostly nontoxic and possess strong antioxidant activity.

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-8633131281437175352009-08-25T15:50:00.001-07:002009-08-25T15:50:14.119-07:00

Facial Plast Surg Clin North Am. 2009 Aug; 17(3): 469-487.e3Brenner MJ, Perro CAResidual disfigurement is a common problem for patients who have undergone skin cancer reconstruction. Restoring form and function in these patients is an artistic and technical endeavor. The efficacy of surgical scar revision, dermabrasion, chemical peels, and laser resurfacing is predicated upon the skin's innate

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-69052972788101338702009-08-25T02:25:00.001-07:002009-08-25T02:25:12.743-07:00

J Epidemiol. 2009 Aug 22; Asakura K, Nishiwaki Y, Milojevic A, Michikawa T, Kikuchi Y, Nakano M, Iwasawa S, Hillebrand G, Miyamoto K, Ono M, Kinjo Y, Akiba S, Takebayashi TBackground: The number of studies that use objective and quantitative methods to evaluate facial skin aging in elderly people is extremely limited, especially in Japan. Therefore, in this cross-sectional study we attempted to

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-70347428394469238932009-08-23T23:29:00.001-07:002009-08-23T23:29:25.194-07:00

J Investig Dermatol Symp Proc. 2009 Aug; 14(1): 25-31Gilchrest BA, Eller MS, Yaar MUV-induced melanogenesis (tanning) and "premature aging" or photoaging result in large part from DNA damage. This article reviews data tying both phenomena to telomere-based DNA damage signaling and develops a conceptual framework in which both responses may be understood as cancer-avoidance protective

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-6964910571092775252009-08-23T07:23:00.001-07:002009-08-23T07:23:43.757-07:00

J Appl Physiol. 2009 Aug 13; Hess KL, Wilson TE, Sauder CL, Gao Z, Ray CA, Monahan KDCardiovascular-related mortality peaks during cold winter months, particularly in older adults. Acute physiological responses, such as increases in blood pressure, in response to cold exposure may contribute to these associations. To determine if the blood pressure raising effect (pressor response) of acute

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-32210787735191964062009-08-23T00:17:00.001-07:002009-08-23T00:17:44.896-07:00

Age (Dordr). 2009 Aug 21; Ford CT, Sherratt MJ, Griffiths CE, Watson REAging in human skin is the composite of time-dependent intrinsic aging plus photoaging induced by chronic exposure to ultraviolet radiation. Nuclear hormone receptors coordinate diverse processes including metabolic homeostasis. Liver X receptor beta (LXRbeta) is a close human homologue of daf-12, a regulator of nematode

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-24990633535174722552009-08-22T21:30:00.001-07:002009-08-22T21:30:33.709-07:00

Gerontology. 2009 Aug 20; Kunz M, Mylius V, Schepelmann K, Lautenbacher SBackground: Both age and dementia have been shown to have an effect on nociception and pain processing. The question arises whether mild cognitive impairment (MCI), which is thought to be a transitional stage between normal ageing and dementia, is also associated with alterations in pain processing. Objective: The aim of

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-47038065183747249752009-08-22T17:49:00.001-07:002009-08-22T17:49:10.415-07:00

An Bras Dermatol. 2009 Jul; 84(3): 263-9Montagner S, Costa AAs a result of the increase in life expectancy, the study of the organic process of aging has been stimulated. Skin ageing, which reflects the signs of time, is a time-dependent process of progressive deterioration that can be intensified by sun exposure, which is known as photoaging. The damage of radiation on various cell structures

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-59029207048215277362009-08-21T18:53:00.001-07:002009-08-21T18:53:08.337-07:00

Am J Med Genet A. 2009 Aug 13; Al-Dosari M, Alkuraya FSEffect of aging on decreased skin elasticity and bone mass is well known. Geroderma osteodysplastica (GO) is a very rare autosomal recessive disorder that recapitulates these two phenotypes at a much younger age. Using homozygosity mapping and linkage analysis in four Saudi families we have identified two mutations in SCYL1BP1, consistent

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-6999930282481624082009-08-20T20:54:00.001-07:002009-08-20T20:54:49.544-07:00

Postgrad Med. 2001 Feb; 109(2 Suppl): 70-7Bonomo RAInfectious diseases in the institutionalized elderly are emerging as 1 of the major issues challenging physicians treating adult patients. The most common syndromes encountered are nursing home-acquired pneumonia, urinary tract infections, and skin and soft tissue infections. As a complicating factor, immunocompromised elderly patients are often

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-62871816547940244452009-08-20T17:47:00.001-07:002009-08-20T17:47:56.832-07:00

Pigment Cell Melanoma Res. 2009 Aug 4; Vanover JC, Spry ML, Hamilton L, Wakamatsu K, Ito S, D'Orazio JAAbstract The K14-SCF transgenic murine model of variant pigmentation is based on epidermal expression of stem cell factor (SCF) on the C57BL/6J background. In this system, constitutive expression of SCF by epidermal keratinocytes results in retention of melanocytes in the interfollicular basal

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-56778369736848372562009-08-20T07:42:00.001-07:002009-08-20T07:42:40.823-07:00

Braz Oral Res. 2009 Apr-Jun; 23(2): 144-8Mancuso DN, Goiato MC, dos Santos DMOne of the greatest challenges faced by buccomaxillofacial prosthetists is to reproduce the patient's exact skin color and provide adequate esthetics. To reach this objective, professionals must use materials with easy characterization and that maintain color over long periods of time. The objective of this study was,

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-90279264650941902052009-08-20T00:05:00.001-07:002009-08-20T00:05:32.296-07:00

J Investig Dermatol Symp Proc. 2009 Aug; 14(1): 8-14Kamenisch Y, Berneburg MProgeroid syndromes are a group of diseases characterized by signs of premature aging. These syndromes comprise diseases such as Werner syndrome, Bloom syndrome, Rothmund-Thomson syndrome, Hutchinson-Gilford syndrome, Fanconi anemia, and ataxia-telangiectasia, as well as xeroderma pigmentosum, trichothiodystrophy, and

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-18309006549663810052009-08-19T21:59:00.001-07:002009-08-19T21:59:22.053-07:00

J Drugs Dermatol. 2009 Aug; 8(8): 708-12Tanaka Y, Matsuo K, Yuzuriha SBACKGROUND: Infrared irradiation stimulates collagen production, but histological differences in its long-term effects on type I versus type III collagen and elastin in human tissue are unclear. OBJECTIVE: To investigate the effects of infrared irradiation. METHODS AND MATERIALS: In vivo human tissues in sun-protected and

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-51867147363613441302009-08-19T17:34:00.001-07:002009-08-19T17:34:23.299-07:00

J Investig Dermatol Symp Proc. 2009 Aug; 14(1): 44-9Krutmann J, Schroeder PThe exact pathogenesis of photoaging of the skin is not yet known. Earlier, a number of molecular pathways explaining one or more characteristics of photoaged skin have been described, but a unifying mechanistic concept is still missing. Here we propose the "Defective Powerhouse Model of Premature Skin Aging", which

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-42436986048473271112009-08-19T00:29:00.001-07:002009-08-19T00:29:37.862-07:00

J Investig Dermatol Symp Proc. 2009 Aug; 14(1): 15-9Cho S, Shin MH, Kim YK, Seo JE, Lee YM, Park CH, Chung JHSunlight damages human skin, resulting in a wrinkled appearance. Since natural sunlight is polychromatic, its ultimate effects on the human skin are the result of not only the action of each wavelength separately, but also interactions among the many wavelengths, including UV, visible

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-18464500270949257012009-08-18T02:20:00.001-07:002009-08-18T02:20:02.997-07:00

J Investig Dermatol Symp Proc. 2009 Aug; 14(1): 20-4Quan T, Qin Z, Xia W, Shao Y, Voorhees JJ, Fisher GJUV radiation from the sun impacts skin health adversely through complex, multiple molecular pathways. Premature skin aging (photoaging) is among the most widely appreciated harmful effects of chronic exposure to solar UV radiation. Extensive damage to the dermal connective tissue is a hallmark

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-23201495469654487582009-08-17T23:25:00.001-07:002009-08-17T23:25:51.242-07:00

J Investig Dermatol Symp Proc. 2009 Aug; 14(1): 2-7Amano SAging of sun-exposed skin is accelerated by three major environmental factors: UV radiation, dryness, and oxidation. UV radiation exposure is the most influential factor in skin aging (so-called photoaging). To find ways to protect against damage caused by UV exposure and to delay photoaging, we studied internal changes of sun-exposed

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-88573271944481051782009-08-17T05:50:00.001-07:002009-08-17T05:50:27.174-07:00

J Investig Dermatol Symp Proc. 2009 Aug; 14(1): 56-9Matsui MS, Hsia A, Miller JD, Hanneman K, Scull H, Cooper KD, Baron EThe association between ultraviolet radiation (UVR) exposure and both skin cancer and photo-aging is well documented. In addition to the conventional organic-chemical and physical-mineral type sunscreens, other non-sunscreen protective strategies have been developed. These

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-1827264223912671142009-08-16T22:57:00.000-07:002009-08-16T22:58:02.640-07:00

J Investig Dermatol Symp Proc. 2009 Aug; 14(1): 36-43Imokawa GIn clinical studies, the formation of facial wrinkles has been closely linked to the loss of elastic properties of the skin. Repetitive irradiation of animal skin with UVB radiation at suberythemal doses significantly reduces its elastic properties, resulting in the formation of wrinkles. Repetitive UVB irradiation elicits a marked

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-1729428700340190882009-08-15T22:56:00.001-07:002009-08-15T22:56:40.454-07:00

J Investig Dermatol Symp Proc. 2009 Aug; 14(1): 53-5Morita A, Torii K, Maeda A, Yamaguchi YAlthough it is now widely recognized that tobacco smoke has negative effects on the skin, the molecular mechanisms underlying its skin-aging effects remain uncertain. Epidemiological studies indicate that tobacco smoking is a strong independent predictor of facial wrinkle formation and other aspects of

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-84704552356048379782009-08-13T17:36:00.001-07:002009-08-13T17:36:09.043-07:00

Age (Dordr). 2009 Aug 11; Gonzales P, Rikke BAAging leads to a loss of thermoregulation that can be readily monitored in laboratory mice. However, it is unclear from previous studies-we provide a tabular summary of 15 articles-whether significant loss occurs by midlife ( approximately 15 months of age). In this study, we examined 34 females from 22 LSXSS strains starting at 4 and 8 months of age

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-49621423267844978112009-08-12T17:35:00.001-07:002009-08-12T17:35:26.951-07:00

J Struct Biol. 2009 Aug 7; Youn HS, Shin TJSupramolecular assembly of collagen fibrils into collagen fiber and its distribution in fish scales of red seabream, Pagrus major, were investigated. By virtue of Zernike phase-contrast hard x-ray microscopy, it has been firstly observed that collagen fiber consists of helical substructures of collagen fibrils wrapped with incrustation. As it close to

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-10135287254811138152009-08-12T06:37:00.001-07:002009-08-12T06:37:34.096-07:00

J Exp Med. 2009 Aug 10; Agius E, Lacy KE, Vukmanovic-Stejic M, Jagger AL, Papageorgiou AP, Hall S, Reed JR, Curnow SJ, Fuentes-Duculan J, Buckley CD, Salmon M, Taams LS, Krueger J, Greenwood J, Klein N, Rustin MH, Akbar ANImmunity declines during aging, however the mechanisms involved in this decline are not known. In this study, we show that cutaneous delayed type hypersensitivity (DTH)

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-31334181676151054882009-08-09T17:24:00.001-07:002009-08-09T17:24:59.794-07:00

Forensic Sci Med Pathol. 2009 Aug 5; Gibson SJ, Scandrett CM, Solomon CJ, Maylin MI, Wilkinson CMA computer assisted method for altering the perceived age of a human face is presented. Our technique is based on calculating a trajectory or axis within a multi-dimensional space that captures the changes in large scale facial structure, shading and complexion associated with aging. Fine facial

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-53225721180895575732009-08-09T15:41:00.001-07:002009-08-09T15:41:55.208-07:00

Cancer Biol Ther. 2009 Oct 6; 8(19): Li J, Chigurupati S, Agarwal R, Mughal MR, Mattson MP, Becker KG, Wood WH, Zhang Y, Morin PJClaudin proteins are frequently overexpressed in various tumors such as breast, prostate and ovarian cancer. While their functions in cancer have not been completely elucidated, roles in survival, adhesion and invasion have been suggested. In order to clarify the roles

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-91893922304860134202009-08-09T07:19:00.001-07:002009-08-09T07:19:29.881-07:00

Toxicol Ind Health. 2009 May; 25(4-5): 231-9Pavlou P, Rallis M, Deliconstantinos G, Papaioannou G, Grando SInhaled tobacco smoke comes in direct contact with few organs such as mouth, lungs, and stomach. Cigarette smoke (CS) in lungs has been extensively studied. However, limited data exist on its effect on skin, and there are no long-term experimental studies suggesting toxic effects on skin.

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-15719644984180950612009-08-09T06:56:00.001-07:002009-08-09T06:56:32.857-07:00

Am J Pathol. 2009 Aug 6; Majora M, Wittkampf T, Schuermann B, Schneider M, Franke S, Grether-Beck S, Wilichowski E, Bernerd F, Schroeder P, Krutmann JDeletions within the mitochondrial DNA (mtDNA) are thought to contribute to extrinsic skin aging. To study the translation of mtDNA deletions into functional and structural changes in the skin, we seeded human skin fibroblasts into collagen gels to

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-44023184349791709402009-08-08T01:04:00.001-07:002009-08-08T01:04:04.226-07:00

Toxicol Ind Health. 2009 May; 25(4-5): 241-7Valacchi G, Pecorelli A, Mencarelli M, Maioli E, Davis PBeta-carotene has been thought to protect against oxidative stress generated by ultraviolet radiation and thus prevents skin cancer and skin aging (Biesalski and Obermueller-Jevic, 2001). However, nothing is known about its potential effects against other environmental sources of oxidative stress

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-72909325009296791172009-08-07T16:13:00.001-07:002009-08-07T16:13:14.514-07:00

Wien Klin Wochenschr. 2009; 121(13-14): 431-9Pavicic T, Steckmeier S, Kerscher M, Korting HCAs well as for topically used dermatological agents, studies performed according to the rules of evidence-based medicine (EBM) are also needed for cosmetics. Although the concept of evidence-based cosmetics has been only partly developed so far, there are some agents and preparations available that can be

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-66780378999651257462009-08-04T04:49:00.001-07:002009-08-04T04:49:44.941-07:00

Skin Pharmacol Physiol. 2009 Jul 31; 22(4): 200-209Bellemère G, Stamatas GN, Bruère V, Bertin C, Issachar N, Oddos TThe antiaging efficacy of retinol (ROL) has been explored mainly clinically in photoprotected skin sites and for high doses of ROL (0.4-1.6%). The objective of the study was to demonstrate the antiaging action of a low and tolerable dose of ROL (0.1%) ex vivo by measuring the

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-39612476354942213392009-08-04T03:11:00.000-07:002009-08-04T03:12:01.080-07:00

J Ethnopharmacol. 2009 Jul 18; Hsu MF, Chiang BHETHNOPHARMACOLOGICAL RELEVANCE: Radix astragali, a well-known Chinese herb, which has been traditionally used for skincare, and microbial fermentation is one of the conventional methods for processing Chinese herbs. AIM OF THE STUDY: This research studied the effects of non-fermented (HQNB) and fermented preparations (HQB) of Radix astragali on

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-56589786757748324352009-07-31T20:48:00.001-07:002009-07-31T20:48:01.380-07:00

FASEB J. 2009 Jul 29; Salem MM, Shalbaf M, Gibbons NC, Chavan B, Thornton JM, Schallreuter KUVitiligo is characterized by a patchy loss of inherited skin color affecting approximately 0.5% of individuals of all races. Despite the absence of the protecting pigment and the overwhelming evidence for hydrogen peroxide (H2O2)-induced oxidative stress in the entire epidermis of these patients, there

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-39908695636368049312009-07-30T20:59:00.001-07:002009-07-30T20:59:14.669-07:00

Consult Pharm. 2009 Jun; 24 Suppl B: 5-10Drab SROBJECTIVES: To identify the incidence and symptoms of type 2 diabetes in older adult patients, review appropriate glycemic targets for older adults with type 2 diabetes, and consider the rationale for managing hyperglycemia in this patient population. DATA SOURCES: Live symposium presentation based on clinical practice and research, medical

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-22900797903187899682009-07-29T22:53:00.001-07:002009-07-29T22:53:25.816-07:00

J Drugs Dermatol. 2009 Jul; 8(7 Suppl): s3Weinkle SH, Tiesman JP

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-79660022780628286872009-07-29T17:28:00.001-07:002009-07-29T17:28:48.864-07:00

J Drugs Dermatol. 2009 Jul; 8(7 Suppl): s4-7Osborne R, Mullins LA, Jarrold BBGlobal gene expression profiling provides a useful means to identify key aspects of the skin aging process, and provides information to help develop new skin technologies. Important aspects of skin aging that can be addressed include skin hydration, barrier, matrix, pigmentation and antioxidant capacity. Human skin

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-63545566052011789032009-07-29T06:36:00.001-07:002009-07-29T06:36:37.651-07:00

J Drugs Dermatol. 2009 Jul; 8(7 Suppl): s15-8Kaczvinsky JR, Grimes PESkin aging integrates the impact of extrinsic skin insults (e.g., ultraviolet [UV] light, etc.) with chronological, genetically programmed decreases in cellular function. A genomic study of aged skin highlighted the mechanistic importance of skin barrier function, exfoliation, control of reactive oxygen species and maintenance

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-17854050390005433132009-07-29T02:30:00.001-07:002009-07-29T02:30:48.502-07:00

J Drugs Dermatol. 2009 Jul; 8(7 Suppl): s8-11Robinson MK, Binder RL, Griffiths CELike all tissues, the skin ages due to the passage of time (chronologic aging). However, skin is also exposed to external insults, such as sunlight. Aging due to chronic sun exposure (photoaging) is characterized clinically by wrinkling, dyspigmentation and other changes. Chronologic and photoaging of skin have been

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-74158407114374986382009-07-28T23:25:00.001-07:002009-07-28T23:25:51.197-07:00

J Cosmet Laser Ther. 2009 Jul 22; 1-5Chiba C, Usui A, Hara H, Ishi YBackground: The long-pulse Nd:YAG laser is a versatile, effective and safe treatment modality for skin rejuvenation, in addition to the treatments of telangiectasia and laser hair removal. Objective: To evaluate the clinical efficacy and safety of a long-pulse Nd:YAG laser for skin rejuvenation in Japanese patients. Methods: A

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-49680148770472169892009-07-28T18:55:00.001-07:002009-07-28T18:55:45.171-07:00

J Med Food. 2009 Jun; 12(3): 601-7Shim JS, Choi EJ, Lee CW, Kim HS, Hwang JKMatrix metalloproteinase (MMP)-1 is a superfamily of zinc-dependent endopeptidases that are capable of degrading all components of the extracellular matrix. Kaempferia pandurata extract (0.01-0.5 microg/mL) significantly reduced the expression of MMP-1 and induced the expression of type 1 procollagen at the protein and

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-87301913524364560602009-07-28T17:30:00.001-07:002009-07-28T17:30:18.555-07:00

Skin Res Technol. 2009 Aug; 15(3): 357-63Koehler MJ, Preller A, Kindler N, Elsner P, König K, Bückle R, Kaatz MBACKGROUND: Skin aging is accelerated by extrinsic factors, particularly actinic damage. Over the last decades, both clinical and pathological differences between intrinsic and actinic aging have been characterized. In this work, we aimed at quantifying skin aging by non-invasive in

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-70874573049190649332009-07-28T07:34:00.001-07:002009-07-28T07:34:11.287-07:00

Int J Cosmet Sci. 2009 Jul 17; Fujimura T, Sugata K, Haketa K, Hotta MSynopsis Visual scoring has been used to evaluate ethnic differences in skin wrinkling, but it is not sufficient to fully evaluate those differences in wrinkles. We examined whether both the roughness analysis of the skin and visual scoring are sufficient to characterize ethnic differences in wrinkles in Japanese, Chinese and

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-43142189430369246222009-07-27T23:42:00.001-07:002009-07-27T23:42:16.263-07:00

Skin Res Technol. 2009 Aug; 15(3): 306-13Querleux B, Baldeweck T, Diridollou S, de Rigal J, Huguet E, Leroy F, Holloway Barbosa VBACKGROUND: Ethnic differences in skin structural features have not been thoroughly investigated, and the few reported studies are contradictory. Thus, we have carried out a set of in vivo measurements on the skin of about 400 volunteers from various ethnic origins

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-2314971237194570642009-07-27T15:52:00.000-07:002009-07-27T15:51:59.221-07:00

J Biomed Mater Res B Appl Biomater. 2009 Jul 23; Eleni PN, Krokida MK, Polyzois GL, Gettleman LStatement of Problem: Facial prostheses deteriorate in a service environment primary due to exposition to various environmental factors, including sebaceous oils (sebum) and perspiration. Purpose: This study investigated the physical properties of an experimental, facial prosthetic after immersion for

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-22859118624308254932009-07-26T23:31:00.001-07:002009-07-26T23:31:53.123-07:00

Skin Res Technol. 2009 Aug; 15(3): 299-305Ezure T, Hosoi J, Amano S, Tsuchiya TBACKGROUND/PURPOSE: Facial sagging is associated with aging, although the mechanism remains unclear. The aim of this study was to investigate the mechanism of facial sagging by examining the relationship of sagging severity to changes of skin elasticity, fat mass and facial muscle function at the cheek. METHODS: Faces

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-36595914787990520092009-07-24T04:19:00.001-07:002009-07-24T04:19:45.861-07:00

Ann Dermatol Venereol. 2009 May; 136 Suppl 4: S61-6Trevidic P, Cauchois R, Ingallina FThe muscular topographic anatomy of the face has long been known. The functional anatomy of the face has been studied by many neurologists, with Duchenne of Boulogne one of the first. The possibility of correcting not only wrinkles, but also certain regional balances gives botulinum toxin a certain number of

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-74073009599488971142009-07-24T01:46:00.001-07:002009-07-24T01:46:07.547-07:00

Ann Dermatol Venereol. 2009 May; 136 Suppl 4: S146-51Gassia VBotulinum toxin serotype A injections used in treating dynamic wrinkles is one of the least invasive cosmetic procedures. High patient satisfaction and low onset of always moderate side effects contribute to the growing popularity of botulinum toxin injections in cosmetic treatment over the past few years. Years of experience and use,

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-70758369051023888702009-07-23T15:13:00.001-07:002009-07-23T15:13:38.396-07:00

Aesthet Surg J. 2009 May-Jun; 29(3): 174-9Lambros VBACKGROUND: Aging eyes often are treated by excision of apparent excess skin and fat and, in some instances, by elevation of the brow. The result of these traditional approaches is increased definition of the orbit, which is not of benefit for all patients. In some cases, the addition of volume in the periorbital area may provide a

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-38793452142915935172009-07-23T14:01:00.001-07:002009-07-23T14:01:18.672-07:00

Ann Dermatol Venereol. 2009 May; 136 Suppl 4: S111-8Gassia V, Beylot C, Béchaux S, Michaud TAlthough correction of the dynamic wrinkles of the upper part of the face is the major indication for botulinum toxin, there are also many possibilities for the middle and lower thirds of the face and neck. However, these injections are more delicate and require an experienced operator who has excellent

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-22976295995814906292009-07-23T07:00:00.001-07:002009-07-23T07:00:44.729-07:00

Ann Dermatol Venereol. 2009 May; 136 Suppl 4: S67-72Le Louarn CCutaneous ageing is responsible for the increasingly creased appearance of the skin, pores opening, skin dyschromia, while the ageing of the structures of the face is attributed primarily to the effect of gravity on the tissues. The theory expounded below sets out to prove that the main and initial cause of this ageing is the

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-52532846924972570952009-07-23T03:44:00.000-07:002009-07-23T03:45:00.340-07:00

J Ethnopharmacol. 2009 Jul 17; Hsu MF, Chiang BHETHNOPHARMACOLOGICAL RELEVANCE: Radix astragali, a well-known Chinese herb, which has been traditionally used for skincare, and microbial fermentation is one of the conventional methods for processing Chinese herbs. AIM OF STUDY: This research studied the effects of non-fermented (HQNB) and fermented preparations (HQB) of Radix astragali on

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-19080648634971591872009-07-21T17:59:00.001-07:002009-07-21T17:59:40.395-07:00

J Struct Biol. 2009 Jul 15; Robach JS, Stock SR, Veis AMicrostructure of the teeth of the sea urchin Lytechinusvariegatus was investigated using optical microscopy, SEM (scanning electron microscopy) and SIMS (secondary ion mass spectroscopy). The study focused on the internal structure of the first-stage mineral structures of high Mg calcite (primary, secondary and carinar process plates;

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-74514663492027717732009-07-21T08:37:00.001-07:002009-07-21T08:37:18.996-07:00

Regul Toxicol Pharmacol. 2009 Jul 15; Colerangle JBPhotosafety testing has become a necessary component of drug development. Phototoxic effects to human skin can range from sunburn, premature skin aging, to life threatening skin cancer while phototoxic effects to the human eye can range from blurred vision to transient or permanent blindness. Phototoxic liabilities should be recognized early to

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-59197534645266092532009-07-21T05:31:00.001-07:002009-07-21T05:31:55.518-07:00

Neurogastroenterol Motil. 2009 Jul 10; de Iorio F, Malagelada C, Azpiroz F, Maluenda M, Violanti C, Igual L, Vitrià J, Malagelada JRAbstract A programme for evaluation of intestinal motility has been recently developed based on endoluminal image analysis using computer vision methodology and machine learning techniques. Our aim was to determine the effect of intestinal muscle inhibition on wall

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-64295665058211184332009-07-19T18:47:00.001-07:002009-07-19T18:47:06.252-07:00

Semin Cutan Med Surg. 2009 Jun; 28(2): 115-29Talakoub L, Wesley NOThe United States has become progressively more multicultural, with the ethnic population growing at record rates. The US Census Bureau projects that, by the year 2056, greater than 50% of the US population will be of non-Caucasian descent. Ethnic patients have different cosmetic concerns and natural features that are unique. The

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-68544172531528416562009-07-19T16:14:00.001-07:002009-07-19T16:14:58.142-07:00

Aesthet Surg J. 2009 May-Jun; 29(3): 199-206; discussion 206-8Sajjadian A, Guyuron BNasal tip ptosis ("drooping" or long nose) occurs when the tip of the nose is more caudal than what is deemed ideal. Intrinsic factors, such as elongated or caudally-rotated lower lateral cartilages, can lead to nasal tip ptosis. Extrinsic factors, such as elongated upper lateral cartilages or excessive caudal

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-90010674038676231462009-07-15T15:35:00.001-07:002009-07-15T15:35:08.761-07:00

Acta Dermatovenerol Croat. 2009; 17(2): 99-102Matanis E, Munder H, Ullmann Y, Miskin R, Gilhar ACaloric restriction (CR) extends the lifespan of diverse animal species and is currently the only therapeutic intervention known to attenuate aging and increase longevity in laboratory animals. The effect of CR on intrinsic skin aging is not well understood. To study this issue, we took advantage of

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-86440423684620860382009-07-14T02:39:00.001-07:002009-07-14T02:39:16.294-07:00

Nippon Rinsho. 2009 Jul; 67(7): 1277-82Katsuya T, Morishita RWerner's syndrome is a typical progeroid syndrome with many specific features of aging early in life. Clinical features of Werner's syndrome closely resemble accelerated aging, such as cataract, scleroderma skin, diabetes and tumorigenesis. The causative gene of this syndrome is denoted as WRN, which encodes a homolog of the E. coli

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-79760336536538054822009-07-12T18:22:00.001-07:002009-07-12T18:22:21.726-07:00

Biomed Chromatogr. 2009 Jul 9; Lopes LB, Reed RTopical application of lycopene is a convenient way to restore antioxidants depleted from the skin by UV radiation and achieve protection against premature aging and cancer. In this study, a simple, rapid and reproducible method to quantify lycopene in different skin layers was developed, validated and employed to assess this compound after skin

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-23853788503916987002009-07-11T23:29:00.001-07:002009-07-11T23:29:47.783-07:00

J Drugs Dermatol. 2009 Jul; 8(7): 674-7Bergstrom KGIn contrast to youthful skin, mature skin undergoes well-established clinical and microscopic changes, particularly after menopause. In particular, dermal thinning, loss of dermal collagen and decreased lipid production are complicated by the effects of life-long sun exposure. These changes manifest as wrinkling, loss of elasticity, dryness and

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-31645850339034307032009-07-10T18:03:00.001-07:002009-07-10T18:03:12.084-07:00

Int J Cosmet Sci. 2009 Jun; 31(3): 225-35

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-50491738593046317542009-07-10T16:14:00.001-07:002009-07-10T16:14:00.667-07:00

J Invest Dermatol. 2009 Jul 9; Barolet D, Roberge CJ, Auger FA, Boucher A, Germain LIt has been reported that skin aging is associated with a downregulation in collagen synthesis and an elevation in matrix metalloproteinase (MMP) expression. This study investigated the potential of light-emitting diode (LED) treatments with a 660 nm sequentially pulsed illumination formula in the

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-19207642577234187372009-07-09T20:44:00.001-07:002009-07-09T20:44:42.114-07:00

Dis Mon. 2009 Apr; 55(4): 223-35Friedman S, Lippitz J

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-51219322515547048602009-07-08T08:21:00.001-07:002009-07-08T08:21:47.911-07:00

Diabetes Technol Ther. 2009 Jul; 11(7): 461-7Petrofsky JS, McLellan KAbstract Background: Aging and diabetes are both associated with impaired vascular endothelial function. This causes a reduction in the resting blood flow and the blood flow response to autonomic stressors. Further, skin moisture and the ability to sweat are also reduced with aging and diabetes. The present investigation was

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-29335564513838551482009-07-07T21:20:00.001-07:002009-07-07T21:20:35.231-07:00

EuroIntervention. 2009 May; 5(1): 157-65Basalus MW, Ankone MJ, van Houwelingen GK, de Man FH, von Birgelen CAims: To classify and quantify post-expansion irregularities in durable polymer-based coatings of drug-eluting stents (DES). Methods and results: Taxus Liberté, Endeavor Sprint, Endeavor Resolute and Xience V DES (three samples of each) were explored by light microscopy and scanning

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-19436049616632451422009-07-07T18:57:00.001-07:002009-07-07T18:57:22.817-07:00

Phytomedicine. 2009 Jul 3; Sumiyoshi M, Kimura YTurmeric (the rhizomes of Curcuma longa L., Zingiberacease) is widely used as a dietary pigment and spice, and has been traditionally used for the treatment of inflammation, skin wounds and hepatic disorders in Ayurvedic, Unani and Chinese medicine. Although the topical application or oral administration of turmeric is used to improve skin trouble,

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-13634802551832139042009-07-07T16:51:00.001-07:002009-07-07T16:51:25.763-07:00

Am J Hum Genet. 2009 Jul 1; Guernsey DL, Jiang H, Evans SC, Ferguson M, Matsuoka M, Nightingale M, Rideout AL, Provost S, Bedard K, Orr A, Dubé MP, Ludman M, Samuels MEAutosomal-recessive cutis laxa type 2 (ARCL2) is a multisystem disorder characterized by the appearance of premature aging, wrinkled and lax skin, joint laxity, and a general developmental delay. Cutis laxa includes a family of

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-77494060265897031972009-07-06T23:00:00.001-07:002009-07-06T23:00:11.875-07:00

Cell Stem Cell. 2009 Jul 2; 5(1): 64-75Su X, Paris M, Gi YJ, Tsai KY, Cho MS, Lin YL, Biernaskie JA, Sinha S, Prives C, Pevny LH, Miller FD, Flores ERThe cellular mechanisms that regulate the maintenance of adult tissue stem cells are still largely unknown. We show here that the p53 family member, TAp63, is essential for maintenance of epidermal and dermal precursors and that, in its absence,

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-55271153592418859292009-07-06T01:41:00.001-07:002009-07-06T01:41:03.223-07:00

Int J Cosmet Sci. 2009 Jun 30; Udompataikul M, Sripiroj P, Palungwachira PVarious nutraceuticals (dietary supplements) are claimed to have cutaneous antiageing properties, however, there are a limited number of research studies supporting these claims. The objective of this research was to study the effectiveness of an oral nutraceutical containing antioxidants, minerals and glycosaminoglycans

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-59283025728964468452009-07-05T22:31:00.001-07:002009-07-05T22:31:09.847-07:00

Am J Physiol Regul Integr Comp Physiol. 2009 Jul 1; Hodges GJ, Jackson DN, Mattar L, Johnson JM, Shoemaker JKNeuropeptide Y (NPY) is a ubiquitous peptide with multiple effects on energy metabolism, reproduction, neurogenesis, and emotion. In addition, NPY is an important sympathetic neurotransmitter involved in neurovascular regulation. While early studies suggested that the vasoactive effects

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-35107356454631869882009-07-05T19:01:00.001-07:002009-07-05T19:01:44.102-07:00

Acta Reumatol Port. 2009 Apr-Jun; 34(2A): 228-34Azevedo VF, Müller Cde S, Rinaldi L, Bredt MC, Giovanni K, Pereira MA, Volaco FCINTRODUCTION: Systemic Sclerosis (SSc) is an inflammatory disease that decreases functional capacity through muscular atrophy, skin sclerosis and loss of joint function. Scleroderma patients suffer from movement's restriction. In addition, the disease affects the

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-1022933175852477572009-07-05T17:58:00.001-07:002009-07-05T17:58:30.183-07:00

Dermatol Surg. 2009 May; 35(5): 875-7Acikel C, Karagoz H, Kucukodaci Z

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-36966160095475262972009-07-03T21:27:00.001-07:002009-07-03T21:27:17.847-07:00

Plast Surg Nurs. 2008 Jul-Sep; 28(3): 123-8; quiz 129-30Bello JSSun-damaged skin is one of the most common complaints of patients presenting to a plastic surgery or dermatology practice. Baby boomers and many others who chose to sunbathe in their adolescent years previously thought little of the potential damaging effects on their skin and are now "paying the price" (P. Kurtzweil, 1998).

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-56341034531311278242009-07-03T15:27:00.001-07:002009-07-03T15:27:12.993-07:00

Cutis. 2008 Oct; 82(4): 285-90Gerstner G, Matarasso AThere has been an increase in nonsurgical interventions for facial rejuvenation since 2001, which can be attributed to an increase in the use of injectable fillers, volumizers, and biostimulators for soft tissue augmentation. The efficacy and duration of these products depend on their mode of operation, site of injection, and composition.

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-45172451427583523142009-07-03T02:51:00.000-07:002009-07-08T22:44:56.515-07:00

Surgical procedures for tissues damaged by radiation are fraught with the possibility of multiple and serious complications. A knowledge of the altered pathophysiology of such tissues (chiefly diminished blood supply, fibrosis, and direct cellular reparative potential) is necessary for the surgeon to make a proper judgment. Recognition of the pathognomic signs in the skin is important.The

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-28658693639275006722009-07-03T01:59:00.001-07:002009-07-03T01:59:11.066-07:00

J Cutan Med Surg. 2008 Nov-Dec; 12(6): 288-94Housman TS, Berg D, Most SP, Odland PB, Stoddard EBACKGROUND: Distortion of the philtrum, which lends considerable symmetry to the midface, leads to a poor esthetic outcome. OBJECTIVE: This case series describes reconstructive approaches to six philtral defects after Mohs micrographic surgery. Reconstructive approaches including advancement flaps,

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-2386622368610442522009-07-02T23:08:00.001-07:002009-07-02T23:08:18.121-07:00

Indian J Dermatol Venereol Leprol. 2008 Nov-Dec; 74(6): 622-4Kachhawa D, Kalla GBACKGROUND: Various surgical procedures for correcting stable vitiligo exist but these have their own limitations. Autologous, non-cultured, non-trypsinized, melanocyte plus keratinocyte grafting is a new and simple method of vitiligo surgery. OBJECTIVE: The study aimed to evaluate efficacy of a new grafting

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-6826648031989524172009-07-02T15:58:00.001-07:002009-07-02T15:58:02.021-07:00

Curr Opin Ophthalmol. 2009 Jun 24; Lewis CD, Perry JDPURPOSE OF REVIEW: In the last several years, surgeons have increasingly realized the importance of volume loss as a central mechanism of facial aging. New, innovative techniques incorporate volume augmentation, or inflation, to improve cosmetic outcomes. RECENT FINDINGS: Previous rejuvenative facial surgical techniques focused on the removal

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-90025499084112068942009-07-02T15:15:00.000-07:002009-07-08T22:44:57.497-07:00

Current options for treating the aging hand include microdermabrasion, fractional thermolysis, chemical peeling, intense light sources and laser therapy (such as pigment lasers and ablative resurfacing), as well as injectable fillers and volumizers to correct soft tissue atrophy.OBJECTIVE:This article reviews the latest technologies in hand rejuvenation and provides data from three clinical

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-72282801699943859772009-07-02T02:28:00.001-07:002009-07-02T02:28:09.673-07:00

Int J Cosmet Sci. 2009 Jun; 31(3): 240Cho HR, Ryou JH, Lee JW, Lee MHSynopsis Human placental extract is used in the treatment of skin wrinkles and wounds. To date, no studies have evaluated the effects of placental extract on dermal fibroblast proliferation. To investigate the effects of placental extract vs. ascorbic acid on fibroblast proliferation and transforming growth factor (TGF)-beta1

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-22302551352762264742009-07-02T01:49:00.000-07:002009-07-08T22:44:56.776-07:00

Adverse physiologic and biochemical changes in the aging skin are aggravated by unprotected, continuous or repeated exposure to the harmful rays of the sun. Waning hormonal activity contributes to these changes.The associated clinical entities are skin dryness, accentuation of facial lines and wrinkles, hyperpigmentation, and multiple benign or malignant growths. The skin should be protected by

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-85081130988027932892009-07-02T01:46:00.000-07:002009-07-08T22:44:57.041-07:00

A study was made of pigment freckles which recur after skin abrasion of spotted grouped pigmented nevi, according to the lapse of time, chiefly by means of the fluorescence method of Falck and Hillarp.The mechanism of recurrence is summarized as follows. Nearly simultaneously with the epidermal regeneration, dendritic melanin-producing cells derived from hair follicles and eccrine sweat ducts

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-38166781465802108472009-07-01T17:54:00.000-07:002009-07-01T17:53:57.957-07:00

Int J Cosmet Sci. 2009 Jun; 31(3): 237Oba A, Sato C, Takahashi K, Futagawa MThe organs and tissues of the human body function together, and many women know that facial skin quality can be influenced by the condition of other areas. From the perspective of esthetics, the condition of other tissues and organs can have significant impact on facial skin. In our lives, increasing numbers of people

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-73851833329289147682009-07-01T15:11:00.001-07:002009-07-01T15:11:03.934-07:00

J Drugs Dermatol. 2009 May; 8(5 Suppl Skin Rejuenation): 4-13Sundaram H, Mehta RC, Norine JA, Kircik L, Cook-Bolden FE, Atkin DH, Werschler PW, Fitzpatrick RESynergistic interaction of multiple growth factors (GF) in skin controls the processes that promote skin repair. GFs have been shown to affect different pathways of skin repair and rejuvenation with many GFs working in close cooperation

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.comtag:blogger.com,1999:blog-5601379892280382192.post-59149462467958813812009-07-01T02:38:00.001-07:002009-07-01T02:38:36.328-07:00

J Dtsch Dermatol Ges. 2009 Apr 24; Brod C, Schippert W, Breuninger HA 58-year-old man presented in 2001 with dysplastic nevus syndrome with at least 300 nevi and about 100 clinically highly atypical nevi. Three melanomas had been excised by a private dermatologist within the past year. We then removed two additional melanomas. Between 2002 and 2003, 117 nevi which were atypical on dermatoscopy

Slashttp://www.blogger.com/profile/01432494485961524278noreply@blogger.com